Search notes:

System.Runtime.InteropServices.RuntimeEnvironment (class)

The System.Runtime.InteropServices.RuntimeEnvironment class contains a set of static methods that provide information about the Common Language Runtime Environment.

PowerShell

In PowerShell, this information might be queried like so: 
PS C:\> [Runtime.InteropServices.RuntimeEnvironment]::SystemConfigurationFile   # Returns the location of the (system wide) machine.config file
PS C:\> [Runtime.InteropServices.RuntimeEnvironment]::GetRuntimeDirectory()     # Directory where the CLR is installed.
PS C:\> [Runtime.InteropServices.RuntimeEnvironment]::GetSystemVersion()        # Version number of CLR that is is running the current process.

FromGlobalaccessCache

FromGlobalaccessCache tests whether a given assembly is loaded into the Global Assembly Cache, see this PowerShell script

Index