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System.AppDomain (class)

System.AppDomain represents an application domain, that is an an isolated environment where applications execute.
System.AppDomain derives from System.MarshalByRefObject
An application domain is typically created by a runtime host.
An instance of AppDomain is able to respond to the following events
Apparently, on .NET Core, there is exactly one AppDomain (whatever that means).
For each new AppDomain, a default System.Runtime.Remoting.Messaging.CallContext is created.

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Fatal error: Uncaught PDOException: SQLSTATE[HY000]: General error: 8 attempt to write a readonly database in /home/httpd/vhosts/renenyffenegger.ch/php/web-request-database.php:78 Stack trace: #0 /home/httpd/vhosts/renenyffenegger.ch/php/web-request-database.php(78): PDOStatement->execute(Array) #1 /home/httpd/vhosts/renenyffenegger.ch/php/web-request-database.php(30): insert_webrequest_('/notes/Microsof...', 1758187826, '216.73.216.150', 'Mozilla/5.0 App...', NULL) #2 /home/httpd/vhosts/renenyffenegger.ch/httpsdocs/notes/Microsoft/dot-net/namespaces-classes/System/AppDomain(49): insert_webrequest() #3 {main} thrown in /home/httpd/vhosts/renenyffenegger.ch/php/web-request-database.php on line 78